Efficacy and safety of bedaquiline in treatment regimens in patients TB/HV co-infection in the Udmurt Republic

The objective : to evaluate the efficacy and safety of bedaquiline in new chemotherapy regimens HIV-positive tuberculosis patients. Subjects Methods . Treatment results 60 patients with TB/HIV co-infection using treatment containing were analyzed. Results. Patients demonstrated poor adherence treatment, so 46/60 (76.6%) did not complete intensive phase chemotherapy. use cause a critical prolongation QT according ECG results, manifestations arrhythmia, it was well combined ART. Sputum conversion (by culture) registered following cases: by end 2nd month 36/60 (60.0%) patients, 6th – 11/14 (78.6%)